1214-47-7
1214-47-7
Chemical Structure
2′-Hydroxychalcone
- CAS No.: 1214-47-7
- Formula:C15H12O2
- Molecular Weight:224.25
IUPAC Name: 1-(2-Hydroxyphenyl)-3-phenylprop-2-en-1-one
InChIKey: AETKQQBRKSELEL-ZHACJKMWSA-N
SMILES: O=C(C1=C(O)C=CC=C1)/C=C/C2=CC=CC=C2
Biological Activity: 2′-Hydroxychalcone is a hydroxyl derivative of chalcones with anticancer activities. 2'-Hydroxychalcone inhibits NF-κB pathway and induces autophagy and apoptosis in breast cancer cells[1]. 2′-Hydroxychalcone shows a better antifungal activity against the complex Paracoccidioides spp[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2′-Hydroxychalcone | 99.54% | 2′-Hydroxychalcone is a hydroxyl derivative of chalcones with anticancer activities. 2'-Hydroxychalcone inhibits NF-κB pathway and induces autophagy and apoptosis in breast cancer cells. 2′-Hydroxychalcone shows a better antifungal activity against the complex Paracoccidioides spp. | ||||||||||||||||||||
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References
- [1]. Xiao Wang, et al. 2'-Hydroxychalcone Induces Autophagy and Apoptosis in Breast Cancer Cells via the Inhibition of the NF-κB Signaling Pathway: In Vitro and In Vivo Studies. Nutrients. 2024 Feb 13;16(4):514. [Content Brief]
- [2]. Kaila P Medina-Alarcón, et al. Antifungal activity of 2'-hydroxychalcone loaded in nanoemulsion against Paracoccidioides spp. Future Microbiol. 2020 Jan:15:21-33. [Content Brief]
