1216744-19-2
1216744-19-2
Chemical Structure
GSK4112
Synonym(s): SR6452
- CAS No.: 1216744-19-2
- Formula:C18H21ClN2O4S
- Molecular Weight:396.89
IUPAC Name: tert-butyl N-(4-chlorobenzyl)-N-((5-nitrothiophen-2-yl)methyl)glycinate
InChIKey: WYSLOKHVFKLWOU-UHFFFAOYSA-N
SMILES: ClC1=CC=C(CN(CC2=CC=C([N+]([O-])=O)S2)CC(OC(C)(C)C)=O)C=C1
Biological Activity: GSK4112 (SR6452) is a Rev-erbα agonist with an EC50 value of 0.4 μM. GSK4112 can be used as a chemical tool to probe the function of Rev-erbα in transcriptional repression, regulation of circadian biology, and metabolic pathways[1].
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GSK4112 | 99.31% | GSK4112 (SR6452) is a Rev-erbα agonist with an EC50 value of 0.4 μM. GSK4112 can be used as a chemical tool to probe the function of Rev-erbα in transcriptional repression, regulation of circadian biology, and metabolic pathways. | ||||||||||||||||||||
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