122-18-9
Chemical Structure
Cetalkonium chloride
Synonym(s): Benzyldimethylhexadecylammonium chloride
- CAS No.: 122-18-9
- Formula:C25H46ClN
- Molecular Weight:396.09
IUPAC Name: N-benzyl-N,N-dimethylhexadecan-1-aminium chloride
InChIKey: SXPWTBGAZSPLHA-UHFFFAOYSA-M
SMILES: C[N+](C)(CCCCCCCCCCCCCCCC)CC1=CC=CC=C1.[Cl-]
Biological Activity: Cetalkonium chloride is an ammonium antiseptic agent used in many topical agents for infections of mouth, throat and eye. Cetalkonium chloride acts as anti-inflammatory amphiphilic agent. Cetalkonium chloride is a cationic surfactant, that improves the precorneal residence time and bioavailability of drugs. Cetalkonium chloride interacts with the negative charges on the bacterial cell membrane, disrupts the integrity of the cell membrane, causes leakage of cell contents and ultimately leading to bacterial death[1][2][3].
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Cetalkonium chloride | 99.42% | Cetalkonium chloride is an ammonium antiseptic agent used in many topical agents for infections of mouth, throat and eye. Cetalkonium chloride acts as anti-inflammatory amphiphilic agent. Cetalkonium chloride is a cationic surfactant, that improves the precorneal residence time and bioavailability of drugs. Cetalkonium chloride interacts with the negative charges on the bacterial cell membrane, disrupts the integrity of the cell membrane, causes leakage of cell contents and ultimately leading to bacterial death. | ||||||||||||||||||||
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Cetalkonium chloride (Standard) | ≥98% | Cetalkonium (chloride) (Standard) is the analytical standard of Cetalkonium (chloride). This product is intended for research and analytical applications. Cetalkonium chloride is an ammonium antiseptic agent used in many topical agents for infections of mouth, throat and eye. Cetalkonium chloride acts as anti-inflammatory amphiphilic agent. Cetalkonium chloride is a cationic surfactant, that improves the precorneal residence time and bioavailability of drugs. Cetalkonium chloride interacts with the negative charges on the bacterial cell membrane, disrupts the integrity of the cell membrane, causes leakage of cell contents and ultimately leading to bacterial death. | ||||||||||||||||||||
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Cetalkonium chloride-d7 | Cetalkonium Chloride-d7 is the deuterium labeled Cetalkonium Chloride. | |||||||||||||||||||||
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Cetalkonium-d5 chloride | Cetalkonium-d5 chloride (Benzyldimethylhexadecylammonium-d5 chloride) is the deuterium labeled Cetalkonium chloride (HY-B1597). Cetalkonium chloride is an ammonium antiseptic agent used in many topical agents for infections of mouth, throat and eye. Cetalkonium chloride acts as anti-inflammatory amphiphilic agent. Cetalkonium chloride is a cationic surfactant, that improves the precorneal residence time and bioavailability of drugs. Cetalkonium chloride interacts with the negative charges on the bacterial cell membrane, disrupts the integrity of the cell membrane, causes leakage of cell contents and ultimately leading to bacterial death. | |||||||||||||||||||||
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- [1]. Cesar Torres-Luna, et al. Formation of Drug-Participating Catanionic Aggregates for Extended Delivery of Non-Steroidal Anti-Inflammatory Drugs from Contact Lenses. Biomolecules. 2019 Oct 10;9(10):593. [Content Brief]
- [2]. Daull P, et al., Benefits of cetalkonium chloride cationic oil-in-water nanoemulsions for topical ophthalmic drug delivery. J Pharm Pharmacol. 2014 Apr;66(4):531-41. [Content Brief]
- [3]. Amangeldykyzy S, et al. The effect of a combined choline salicylate and cetalkonium chloride gel on particular strains of Pseudomonas aeruginosa, Staphylococcus spp. and Streptococcus spp[J]. Current Issues in Pharmacy and Medical Sciences, 2015, 28(2): 78-80.
