122898-67-3
Chemical Structure
Itopride
Synonym(s): HSR803 free base
- CAS No.: 122898-67-3
- Formula:C20H26N2O4
- Molecular Weight:358.43
IUPAC Name: N-(4-(2-(dimethylamino)ethoxy)benzyl)-3,4-dimethoxybenzamide
InChIKey: QQQIECGTIMUVDS-UHFFFAOYSA-N
SMILES: O=C(NCC1=CC=C(OCCN(C)C)C=C1)C2=CC=C(OC)C(OC)=C2
Biological Activity: Itopride (HSR803 free base) is a potent and orally active dopamine-2 antagonist and an acetylcholine esterase (AChE) inhibitor. Itopride enhances gastric motility through both antidopaminergic and anti-acetylcholinesterasic actions, can be used as a gastrointestinal prokinetic agent. Itopride can be used for researching gastro-esophageal reflux disease (GERD)[1].
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Itopride | Itopride (HSR803 free base) is a potent and orally active dopamine-2 antagonist and an acetylcholine esterase (AChE) inhibitor. Itopride enhances gastric motility through both antidopaminergic and anti-acetylcholinesterasic actions, can be used as a gastrointestinal prokinetic agent. Itopride can be used for researching gastro-esophageal reflux disease (GERD). | |||||||||||||||||||||
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Itopride-d6 | Itopride-d6 (HSR803-d6 (free base)) is deuterium labeled Itopride. Itopride (HSR803 free base) is a potent and orally active dopamine-2 antagonist and an acetylcholine esterase (AChE) inhibitor. Itopride enhances gastric motility through both antidopaminergic and anti-acetylcholinesterasic actions, can be used as a gastrointestinal prokinetic agent. Itopride can be used for researching gastro-esophageal reflux disease (GERD). | |||||||||||||||||||||
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Itopride-d4 | Itopride-d4 (HSR803-d4 free base) is the deuterium labeled Itopride (HY-B0732A). Itopride (HSR803 free base) is a potent and orally active dopamine-2 antagonist and an acetylcholine esterase (AChE) inhibitor. Itopride enhances gastric motility through both antidopaminergic and anti-acetylcholinesterasic actions, can be used as a gastrointestinal prokinetic agent. Itopride can be used for researching gastro-esophageal reflux disease (GERD) | |||||||||||||||||||||
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