123318-82-1
Chemical Structure
Clofarabine
- CAS No.: 123318-82-1
- Formula:C10H11ClFN5O3
- Molecular Weight:303.68
IUPAC Name: (2R,3R,4S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
InChIKey: WDDPHFBMKLOVOX-AYQXTPAHSA-N
SMILES: O[C@H]1[C@H](F)[C@H](N(C=N2)C3=C2C(N)=NC(Cl)=N3)O[C@@H]1CO
Biological Activity: Clofarabine, a nucleoside analogue for research of cancer, is a potent inhibitor of ribonucleotide reductase (IC50=65 nM) by binding to the allosteric site on the regulatory subunit[1].
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Clofarabine | 99.83% | Clofarabine, a nucleoside analogue for research of cancer, is a potent inhibitor of ribonucleotide reductase (IC50=65 nM) by binding to the allosteric site on the regulatory subunit. | ||||||||||||||||||||
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Clofarabine (Standard) | ≥98% | Clofarabine (Standard) is the analytical standard of Clofarabine. This product is intended for research and analytical applications. Clofarabine, a nucleoside analogue for research of cancer, is a potent inhibitor of ribonucleotide reductase (IC50=65 nM) by binding to the allosteric site on the regulatory subunit. | ||||||||||||||||||||
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Keywords