123318-82-1

Clofarabine Chemical Structure
123318-82-1

Chemical Structure

Clofarabine

  • CAS No.: 123318-82-1
  • Formula:C10H11ClFN5O3
  • Molecular Weight:303.68

IUPAC Name: (2R,3R,4S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol

InChIKey: WDDPHFBMKLOVOX-AYQXTPAHSA-N

SMILES: O[C@H]1[C@H](F)[C@H](N(C=N2)C3=C2C(N)=NC(Cl)=N3)O[C@@H]1CO

Biological Activity: Clofarabine, a nucleoside analogue for research of cancer, is a potent inhibitor of ribonucleotide reductase (IC50=65 nM) by binding to the allosteric site on the regulatory subunit[1].

Cat. No. Product Name Purity Description Pricing
HY-A0005
Clofarabine 99.83% Clofarabine, a nucleoside analogue for research of cancer, is a potent inhibitor of ribonucleotide reductase (IC50=65 nM) by binding to the allosteric site on the regulatory subunit.
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HY-A0005R
Clofarabine (Standard) ≥98% Clofarabine (Standard) is the analytical standard of Clofarabine. This product is intended for research and analytical applications. Clofarabine, a nucleoside analogue for research of cancer, is a potent inhibitor of ribonucleotide reductase (IC50=65 nM) by binding to the allosteric site on the regulatory subunit.
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