124251-83-8
Chemical Structure
5-Nitro BAPTA
- CAS No.: 124251-83-8
- Formula:C22H23N3O12
- Molecular Weight:521.43
IUPAC Name: potassium 6-amino-2-(5-(2-ammonio-6-((4-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)butyl)amino)hexanamido)pentyl)-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-5,8-disulfonate
InChIKey: JRTCJLPFWVGNQV-UHFFFAOYSA-N
SMILES: O=C(O)CN(C1=CC=CC=C1OCCOC2=CC([N+]([O-])=O)=CC=C2N(CC(O)=O)CC(O)=O)CC(O)=O
Biological Activity: 5-Nitro BAPTA is a calcium chelator, combinded with 2-Me-substituted TM ( as a fluorescent moiety), can be used to form a red fluorescent probe (CaTM-2 AM), for imaging of cytoplasmic Ca2+ in cultured living cells. 5-Nitro BAPTA is a building block used in the synthesis of Ca2+ specific chelators, Ca2+ buffers, and fluorescent Ca2+ indicators[1][2].
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5-Nitro BAPTA | 5-Nitro BAPTA is a calcium chelator, combinded with 2-Me-substituted TM ( as a fluorescent moiety), can be used to form a red fluorescent probe (CaTM-2 AM), for imaging of cytoplasmic Ca2+ in cultured living cells. 5-Nitro BAPTA is a building block used in the synthesis of Ca2+ specific chelators, Ca2+ buffers, and fluorescent Ca2+ indicators. | |||||||||||||||||||||
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- [1]. Takahiro Egawa, et al. Red Fluorescent Probe for Monitoring the Dynamics of Cytoplasmic Calcium Ions†. Angew Chem Int Ed. 2013, 52(14):3874-3877.
- [2]. Jones, et al. Purification and labeling of extracellular vesicles using a mixed mode resin composition: World Intellectual Property Organization, WO2019133842[P]. 2019-07-04.
Keywords
