125-02-0
Chemical Structure
Prednisolone disodium phosphate
Synonym(s): Prednisolone 21-phosphate disodium
- CAS No.: 125-02-0
- Formula:C21H27Na2O8P
- Molecular Weight:484.39
IUPAC Name: sodium 2-((8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl phosphate
InChIKey: VJZLQIPZNBPASX-OJJGEMKLSA-L
SMILES: C[C@@]1([C@@]2(O)C(COP(O[Na])(O[Na])=O)=O)[C@](CC2)([H])[C@@](CCC3=CC4=O)([H])[C@]([C@]3(C=C4)C)([H])[C@@H](O)C1
Biological Activity: Prednisolone disodium phosphate is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Prednisolone disodium phosphate can be rapidly and completely hydrolyzed to Prednisolone in the plasma[1][2][3][4][5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Prednisolone disodium phosphate | 99.50% | Prednisolone disodium phosphate is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Prednisolone disodium phosphate can be rapidly and completely hydrolyzed to Prednisolone in the plasma. | ||||||||||||||||||||
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Prednisolone disodium phosphate (Standard) | 98.98% | Prednisolone (disodium phosphate) (Standard) is the analytical standard of Prednisolone (disodium phosphate). This product is intended for research and analytical applications. | ||||||||||||||||||||
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References
- [1]. Lambrou, G.I., et al., Prednisolone exerts late mitogenic and biphasic effects on resistant acute lymphoblastic leukemia cells: Relation to early gene expression. Leuk Res, 2009. 33(12): p. 1684-95. [Content Brief]
- [2]. http://en.wikipedia.org/wiki/Prednisolone
- [3]. Mooren FC, et al. Influence of chitosan microspheres on the transport of prednisolone sodium phosphate across HT-29 cell monolayers. Pharm Res. 1998 Jan;15(1):58-65. [Content Brief]
- [4]. Musson DG, et al. Comparative corneal penetration of prednisolone sodium phosphate and prednisolone acetate in NZW rabbits. J Ocul Pharmacol. 1991 Summer;7(2):175-82. [Content Brief]
- [5]. Boudinot FD, et al. Dose-dependent pharmacokinetics of prednisolone in normal and adrenalectomized rats. J Pharmacokinet Biopharm. 1986 Oct;14(5):453-67. [Content Brief]
