1263477-83-3
1263477-83-3
Chemical Structure
LPT99
- CAS No.: 1263477-83-3
- Formula:C31H32Cl2N4O4S
- Molecular Weight:627.58
InChIKey: XLXXBYJYWULGGD-UHFFFAOYSA-N
SMILES: O=C(CC1C(N(CCC2=CC=C(C=C2Cl)Cl)CC(N1CCC3=CC=CS3)=O)=O)NCCC4=CNC5=C4C=C(OC)C=C5
Biological Activity: LPT-99 is an antagonist of apoptotic protease activating factor 1 (APAF-1). LPT-99 suppresses the activation of procaspase-9. LPT99 suppresses Cisplatin (HY-17394)-induced apoptosis. LPT99 can effectively mitigate cisplatin-induced hearing loss in rats.[1]
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LPT99 | LPT-99 is an antagonist of apoptotic protease activating factor 1 (APAF-1). LPT-99 suppresses the activation of procaspase-9. LPT99 suppresses Cisplatin (HY-17394)-induced apoptosis. LPT99 can effectively mitigate cisplatin-induced hearing loss in rats. | |||||||||||||||||||||
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References
Keywords
