127951-99-9
127951-99-9
Chemical Structure
Hydrodolasetron
- CAS No.: 127951-99-9
- Formula:C19H22N2O3
- Molecular Weight:326.39
IUPAC Name: 3-hydroxyoctahydro-2H-2,6-methanoquinolizin-8-yl 1H-indole-3-carboxylate
InChIKey: MLWGAEVSWJXOQJ-UHFFFAOYSA-N
SMILES: O=C(C1=CNC2=C1C=CC=C2)OC3CC4N5CC(O)C(C4)CC5C3
Biological Activity: Hydrodolasetron is a metabolite of Dolasetron (HY-B0750). Hydrodolasetron is more potent than Dolasetron in inhibiting nAChR. Hydrodolasetron is a 5-HT(3A)R blocker with an IC50 of 0.29 nM. Hydrodolasetron has antiemetic activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Hydrodolasetron | 98.96% | Hydrodolasetron is a metabolite of Dolasetron (HY-B0750). Hydrodolasetron is more potent than Dolasetron in inhibiting nAChR. Hydrodolasetron is a 5-HT(3A)R blocker with an IC50 of 0.29 nM. Hydrodolasetron has antiemetic activity. | ||||||||||||||||||||
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Hydrodolasetron-d5 | Hydrodolasetron-d5 is deuterated labeled Hydrodolasetron. | |||||||||||||||||||||
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Hydrodolasetron-d4 | Hydrodolasetron-d4 is deuterium labeled Hydrodolasetron. | |||||||||||||||||||||
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References
