129263-59-8
129263-59-8
Chemical Structure
(5S,6R)-DiHETEs
Synonym(s): (5S,6R)-(11E)-DiHETE
- CAS No.: 129263-59-8
- Formula:C20H32O4
- Molecular Weight:336.47
IUPAC Name: (5S,6R,7E,9E,11E,14Z)-5,6-dihydroxyicosa-7,9,11,14-tetraenoic acid
InChIKey: UVZBUUTTYHTDRR-QLMKOMRNSA-N
SMILES: CCCCC/C=C\C/C=C/C=C/C=C/[C@@H](O)[C@@H](O)CCCC(O)=O
Biological Activity: (5S,6R)-DiHETEs is the isomer of (5S,6R)-DiHETE (HY-130138A). (5S,6R)-DiHETE can be recognized by leukotriene receptors (LTD4 receptors). (5S,6R)-DiHETE can induce guinea pig isolated ileum contraction with an EC50 of 1.3 μM, and this effect can be inhibited by LTD4 receptor antagonists[1].
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(5S,6R)-DiHETEs | (5S,6R)-DiHETEs is the isomer of (5S,6R)-DiHETE (HY-130138A). (5S,6R)-DiHETE can be recognized by leukotriene receptors (LTD4 receptors). (5S,6R)-DiHETE can induce guinea pig isolated ileum contraction with an EC50 of 1.3 μM, and this effect can be inhibited by LTD4 receptor antagonists. | |||||||||||||||||||||
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