129648-96-0
Chemical Structure
KT2-962
- CAS No.: 129648-96-0
- Formula:C23H25ClNNaO5S2
- Molecular Weight:518.02
IUPAC Name: sodium 3-(4-((4-chlorophenyl)sulfonamido)butyl)-6-isopropylazulene-1-sulfonate
InChIKey: QIBQVFYOTMPEIP-UHFFFAOYSA-M
SMILES: O=S(C1=C2C=CC(C(C)C)=CC=C2C(CCCCNS(=O)(C3=CC=C(C=C3)Cl)=O)=C1)(O[Na])=O
Biological Activity: KT2-962 is a thromboxane A2 (TXA2) receptor antagonist and potent hydroxyl radical scavenger (IC50=500 nM). KT2-962 reduces myocardial infarct size and ventricular fibrillation. KT2-962 demonstrates cardioprotective effect in a canine ischemia/reperfusion model. KT2-962 is promising for research of myocardial ischemia-reperfusion injury and TXA2-mediated vascular diseases[1].
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KT2-962 | KT2-962 is a thromboxane A2 (TXA2) receptor antagonist and potent hydroxyl radical scavenger (IC50=500 nM). KT2-962 reduces myocardial infarct size and ventricular fibrillation. KT2-962 demonstrates cardioprotective effect in a canine ischemia/reperfusion model. KT2-962 is promising for research of myocardial ischemia-reperfusion injury and TXA2-mediated vascular diseases. | |||||||||||||||||||||
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Keywords
