129748-28-3
129748-28-3
Chemical Structure
Cerpegin
- CAS No.: 129748-28-3
- Formula:C10H11NO3
- Molecular Weight:193.20
SMILES: O=C1OC(C)(C)C(C=CN2C)=C1C2=O
Biological Activity: Cerpegin, a pyridinone-fused c-lactone, is an inhibitor of 20S proteasome. Cerpegin can be used as a tranquillizer, anti-inflammatory, analgesic and antiulcer[1][2].
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Cerpegin | Cerpegin, a pyridinone-fused c-lactone, is an inhibitor of 20S proteasome. Cerpegin can be used as a tranquillizer, anti-inflammatory, analgesic and antiulcer. | |||||||||||||||||||||
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References
- [1]. Anna Hovhannisyan, et al. New C(4)- and C(1)-derivatives of furo[3,4-c]pyridine-3-ones and related compounds: evidence for site-specific inhibition of the constitutive proteasome and its immunoisoform. Bioorg Med Chem Lett. 2014 Mar 15;24(6):1571-80. [Content Brief]
- [2]. K. Sivakumar, et al. Structure of cerpegin, a new alkaloid. Acta Cryst. (1990). C46, 839-841.
