130775-79-0
130775-79-0
Chemical Structure
MS-153
- CAS No.: 130775-79-0
- Formula:C10H11N3O
- Molecular Weight:189.21
IUPAC Name: (R)-(5-methyl-4,5-dihydro-1H-pyrazol-1-yl)(pyridin-3-yl)methanone
InChIKey: KKMMIKKVFRCZBO-MRVPVSSYSA-N
SMILES: C[C@@H]1CC=NN1C(C2=CN=CC=C2)=O
Biological Activity: MS-153 is a glutamate transporter activator that can be used as a neuroprotective agent[1][2].
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MS-153 | MS-153 is a glutamate transporter activator that can be used as a neuroprotective agent. | |||||||||||||||||||||
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References
- [1]. Shimada F, et al. The neuroprotective agent MS-153 stimulates glutamate uptake. Eur J Pharmacol. 1999 Dec 15;386(2-3):263-70. [Content Brief]
- [2]. Nakagawa T, et al. Inhibition of morphine tolerance and dependence by MS-153, a glutamate transporter activator. Eur J Pharmacol. 2001 May 4;419(1):39-45. [Content Brief]
