13187-06-9
Chemical Structure
Pimethixene maleate
Synonym(s): Pimetixene maleate
- CAS No.: 13187-06-9
- Formula:C23H23NO4S
- Molecular Weight:409.50
IUPAC Name: 1-methyl-4-(9H-thioxanthen-9-ylidene)piperidine maleate
InChIKey: IPANUAHQWFDVAG-BTJKTKAUSA-N
SMILES: CN1CC/C(CC1)=C2C3=C(SC4=C\2C=CC=C4)C=CC=C3.OC(/C=C\C(O)=O)=O
Biological Activity: Pimethixene maleate is antihistamine and antiserotonergic compound, acts as an antimigraine agent. Pimethixene maleate is a highly potent antagonist of 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors, with pKis of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 and 9.38, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Pimethixene maleate | 99.98% | Pimethixene maleate is antihistamine and antiserotonergic compound, acts as an antimigraine agent. Pimethixene maleate is a highly potent antagonist of 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors, with pKis of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 and 9.38, respectively. | ||||||||||||||||||||
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Pimethixene maleate (Standard) | ≥98% | Pimethixene maleate (Standard) is the analytical standard of Pimethixene maleate. This product is intended for research and analytical applications. Pimethixene maleate is antihistamine and antiserotonergic compound, acts as an antimigraine agent. Pimethixene maleate is a highly potent antagonist of 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors, with pKis of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 and 9.38, respectively. | ||||||||||||||||||||
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Similarity Score 0.82
HY-B1101Pimethixene -
Similarity Score 0.61
HY-32329ARSetiptiline maleate (Standard) -
Similarity Score 0.58
HY-105704Danitracen -
Similarity Score 0.58
HY-B1165Cyproheptadine hydrochloride sesquihydrate -
Similarity Score 0.58
HY-B0366ARCyproheptadine hydrochloride (Standard) -
Similarity Score 0.57
HY-B1622Cyproheptadine -
Similarity Score 0.57
HY-U00021Clothixamide -
Similarity Score 0.57
HY-A0163BZuclopenthixol dihydrochloride -
Similarity Score 0.57
HY-A0163Ctrans-Clopenthixol dihydrochloride -
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