1353219-06-3
1353219-06-3
Chemical Structure
Peficitinib hydrochloride
Synonym(s): ASP015K hydrochloride; JNJ-54781532 hydrochloride
- CAS No.: 1353219-06-3
- Formula:C18H23ClN4O2
- Molecular Weight:362.85
IUPAC Name: 4-(((1R,2s,3S,5s,7s)-5-hydroxyadamantan-2-yl)amino)-1H-pyrrolo[2,3-b]pyridine-5-carboxamide hydrochloride
InChIKey: UQAIDWNFPWQLOC-ZVCJDZAXSA-N
SMILES: O[C@](C[C@@H]1C[C@H]2C3)(C2)C[C@@H]3[C@H]1NC4=C5C(NC=C5)=NC=C4C(N)=O.Cl
Biological Activity: Peficitinib (ASP015K) hydrochloride is an orally active JAK inhibitor, with IC50s of 3.9, 5.0, 0.7 and 4.8 nM for JAK1, JAK2, JAK3 and Tyk2, respectively[1].
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Peficitinib hydrochloride | Peficitinib (ASP015K) hydrochloride is an orally active JAK inhibitor, with IC50s of 3.9, 5.0, 0.7 and 4.8 nM for JAK1, JAK2, JAK3 and Tyk2, respectively. | |||||||||||||||||||||
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References
Keywords
