136765-29-2
136765-29-2
Chemical Structure
Clomipramine-d3
Synonym(s): Chlorimipramine-d3;G-34586-d3;NSC-169865-d3
- CAS No.: 136765-29-2
- Formula:C19H20D3ClN2
- Molecular Weight:317.87
IUPAC Name: 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methyl-N-(methyl-d3)propan-1-amine
InChIKey: GDLIGKIOYRNHDA-FIBGUPNXSA-N
SMILES: ClC1=CC2=C(C=C1)CCC3=C(C=CC=C3)N2CCCN(C([2H])([2H])[2H])C
Biological Activity: Clomipramine-d3 is the deuterium labeled Clomipramine. Clomipramine is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Clomipramine-d3 | Clomipramine-d3 is the deuterium labeled Clomipramine. Clomipramine is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Clomipramine (Standard) | ≥98% | Clomipramine (Standard) is the analytical standard of Clomipramine. This product is intended for research and analytical applications. Clomipramine (Chlorimipramine) is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM. Clomipramine is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Clomipramine | 99.64% | Clomipramine (Chlorimipramine) is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM. Clomipramine is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. McTavish, D. and P. Benfield, Clomipramine. An overview of its pharmacological properties and a review of its therapeutic use in obsessive compulsive disorder and panic disorder. Drugs, 1990. 39(1): p. 136-53. [Content Brief]
- [2]. Owens, M.J., et al., Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther, 1997. 283(3): p. 1305-22. [Content Brief]
