137332-54-8
137332-54-8
Chemical Structure
Tivirapine
Synonym(s): R86183; TIBO R 86183
- CAS No.: 137332-54-8
- Formula:C16H20ClN3S
- Molecular Weight:321.87
IUPAC Name: (S)-5-chloro-8-methyl-7-(3-methylbut-2-en-1-yl)-6,7,8,9-tetrahydro-2,7,9a-triazabenzo[cd]azulene-1(2H)-thione
InChIKey: ZNFFMCYSMBXZQU-NSHDSACASA-N
SMILES: ClC(C1=C2N3C[C@@H](N(C1)C/C=C(C)\C)C)=CC=C2NC3=S
Biological Activity: Tivirapine (R86183) is a nonnucleoside HIV-1 RT inhibitor against HIV-1-induced cytopathic effects with an EC50 value of 4 nM. Tivirapine inhibits the Yl8lC mutant of HIV-1 RT[1].
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Tivirapine | Tivirapine (R86183) is a nonnucleoside HIV-1 RT inhibitor against HIV-1-induced cytopathic effects with an EC50 value of 4 nM. Tivirapine inhibits the Yl8lC mutant of HIV-1 RT. | |||||||||||||||||||||
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References
Keywords
