1373764-75-0
Chemical Structure
YH-306
- CAS No.: 1373764-75-0
- Formula:C19H18N2O2
- Molecular Weight:306.36
IUPAC Name: 2-(4-hydroxyphenyl)-1-(1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)ethan-1-one
InChIKey: WFTJZQLEQGPZBC-UHFFFAOYSA-N
SMILES: OC1=CC=C(C=C1)CC(N2CC(NC3=C4C=CC=C3)=C4CC2)=O
Biological Activity: YH-306 is an antitumor agent. YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway. YH-306 significantly inhibits the migration and invasion of colorectal cancer cells. YH-306 potently suppresses uninhibited proliferation and induces cell apoptosis. YH-306 suppresses the activation of FAK, c-Src, paxillin, and PI3K, Rac1 and the expression of MMP2 and MMP9. YH-306 also inhibita actin-related protein (Arp2/3) complex-mediated actin polymerization[1].
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YH-306 | 98.34% | YH-306 is an antitumor agent. YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway. YH-306 significantly inhibits the migration and invasion of colorectal cancer cells. YH-306 potently suppresses uninhibited proliferation and induces cell apoptosis. YH-306 suppresses the activation of FAK, c-Src, paxillin, and PI3K, Rac1 and the expression of MMP2 and MMP9. YH-306 also inhibita actin-related protein (Arp2/3) complex-mediated actin polymerization. | ||||||||||||||||||||
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