1396257-94-5

Ipatasertib dihydrochloride Chemical Structure
1396257-94-5

Chemical Structure

Ipatasertib dihydrochloride

Synonym(s): GDC-0068 dihydrochloride; RG-7440 dihydrochloride

  • CAS No.: 1396257-94-5
  • Formula:C24H34Cl3N5O2
  • Molecular Weight:530.92

IUPAC Name: (S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one dihydrochloride

InChIKey: SRKVNRNRVFDUTG-VISIQVHMSA-N

SMILES: ClC1=CC=C([C@@H](CNC(C)C)C(N2CCN(C3=C([C@H](C)C[C@H]4O)C4=NC=N3)CC2)=O)C=C1.[H]Cl.[H]Cl

Biological Activity: Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective and ATP-competitive pan-Akt inhibitor with IC50s of 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively.

Cat. No. Product Name Purity Description Pricing
HY-15186A
Ipatasertib dihydrochloride 99.19% Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective and ATP-competitive pan-Akt inhibitor with IC50s of 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively.
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