1396257-94-5
1396257-94-5
Chemical Structure
Ipatasertib dihydrochloride
Synonym(s): GDC-0068 dihydrochloride; RG-7440 dihydrochloride
- CAS No.: 1396257-94-5
- Formula:C24H34Cl3N5O2
- Molecular Weight:530.92
IUPAC Name: (S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one dihydrochloride
InChIKey: SRKVNRNRVFDUTG-VISIQVHMSA-N
SMILES: ClC1=CC=C([C@@H](CNC(C)C)C(N2CCN(C3=C([C@H](C)C[C@H]4O)C4=NC=N3)CC2)=O)C=C1.[H]Cl.[H]Cl
Biological Activity: Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective and ATP-competitive pan-Akt inhibitor with IC50s of 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ipatasertib dihydrochloride | 99.19% | Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective and ATP-competitive pan-Akt inhibitor with IC50s of 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively. | ||||||||||||||||||||
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