140158-50-5
140158-50-5
Chemical Structure
ATPA
- CAS No.: 140158-50-5
- Formula:C10H16N2O4
- Molecular Weight:228.25
IUPAC Name: 2-amino-3-(5-(tert-butyl)-3-oxo-2,3-dihydroisoxazol-4-yl)propanoic acid
InChIKey: PIXJURSCCVBKRF-UHFFFAOYSA-N
SMILES: O=C(O)C(N)CC1=C(C(C)(C)C)ONC1=O
Biological Activity: ATPA is a selective glutamate receptor GluR5 activator with EC50s of 0.66, 9.5, 1.4, 23, 32, 18, and 14 μM for GluR5wt, GluR5(S741M), GluR5(S721T), GluR5(S721T, S741M), GluR5(S741A), GluR5(S741L), and GluR5(S741V), respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ATPA | 98.90% | ATPA is a selective glutamate receptor GluR5 activator with EC50s of 0.66, 9.5, 1.4, 23, 32, 18, and 14 μM for GluR5wt, GluR5(S741M), GluR5(S721T), GluR5(S721T, S741M), GluR5(S741A), GluR5(S741L), and GluR5(S741V), respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.69
HY-103559HexylHIBO -
Similarity Score 0.69
HY-103560(S)-HexylHIBO -
Similarity Score 0.64
HY-19433A(S)-ATPO -
Similarity Score 0.60
HY-W772441H-Phe(3-tBu)-OH hydrochloride -
Similarity Score 0.57
HY-W012133(S)-2-Amino-3-(4-(tert-butoxy)phenyl)propanoic acid -
Similarity Score 0.55
HY-W1024533-(4-Acetylphenyl)-2-aminopropanoic acid hydrochloride -
Similarity Score 0.55
HY-W0122643-O-Methyldopa monohydrate -
Similarity Score 0.55
HY-W0139624-(Trifluoromethyl)-L-phenylalanine -
Similarity Score 0.54
HY-W012214(S)-2-Amino-3-(2-(trifluoromethyl)phenyl)propanoic acid -
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