1420071-30-2
Chemical Structure
Bioymifi
Synonym(s): DR5 Activator
- CAS No.: 1420071-30-2
- Formula:C22H12BrN3O4S
- Molecular Weight:494.32
IUPAC Name: (Z)-5-(5-((3-(4-bromophenyl)-2-imino-4-oxothiazolidin-5-ylidene)methyl)furan-2-yl)isoindoline-1,3-dione
InChIKey: ULBOWKXOFOTCMU-NLDKGBHCSA-N
SMILES: O=C(/C(SC1=N)=C/C2=CC=C(O2)C3=CC(C(N4)=O)=C(C=C3)C4=O)N1C5=CC=C(C=C5)Br
Biological Activity: Bioymifi (DR5 Activator), a potent TRAIL receptor DR5 activator, binds to the extracellular domain (ECD) of DR5 with a Kd of 1.2 μM. Bioymifi can act as a single agent to induce DR5 clustering and aggregation, leading to apoptosis[1].
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Bioymifi | 98.0% | Bioymifi (DR5 Activator), a potent TRAIL receptor DR5 activator, binds to the extracellular domain (ECD) of DR5 with a Kd of 1.2 μM. Bioymifi can act as a single agent to induce DR5 clustering and aggregation, leading to apoptosis. | ||||||||||||||||||||
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Keywords
