1424635-83-5
1424635-83-5
Chemical Structure
TRULI
Synonym(s): Lats-IN-1
- CAS No.: 1424635-83-5
- Formula:C18H14N4OS
- Molecular Weight:334.39
IUPAC Name: (Z)-N-(3-benzylthiazol-2(3H)-ylidene)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide
InChIKey: VTXBMVZVPUSAJF-UZYVYHOESA-N
SMILES: O=C(C1=CNC2=NC=CC=C12)/N=C(SC=C3)/N3CC4=CC=CC=C4
Biological Activity: TRULI (Lats-IN-1) is a potent and ATP-competitive inhibitor of Lats1 and Lats2 kinases. TRULI promotes Yap-dependent proliferation in postmitotic mammalian tissues[1].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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TRULI | 99.30% | TRULI (Lats-IN-1) is a potent and ATP-competitive inhibitor of Lats1 and Lats2 kinases. TRULI promotes Yap-dependent proliferation in postmitotic mammalian tissues. | ||||||||||||||||||||
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TRULI (Standard) | ≥98% | TRULI (Standard) is the analytical standard of TRULI (HY-138489). This product is intended for research and analytical applications. TRULI (Lats-IN-1) is a potent and ATP-competitive inhibitor of Lats1 and Lats2 Kinases. TRULI promotes Yap-dependent proliferation in postmitotic mammalian tissues. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.77
HY-150042TDI-011536 -
Similarity Score 0.51
HY-168897LC3B ligand 1 -
Similarity Score 0.49
HY-124821VA012 -
Similarity Score 0.48
HY-14325BRL-745870 hydrochloride (Standard) -
Similarity Score 0.48
HY-14325L-745870 -
Similarity Score 0.48
HY-14326L-750667 -
Similarity Score 0.47
HY-172171GSK3β-IN-2 -
Similarity Score 0.47
HY-14325AL-745870 trihydrochloride -
Similarity Score 0.47
HY-114539L-750667 triHydrochloride -
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