144754-35-8
144754-35-8
Chemical Structure
S12340
- CAS No.: 144754-35-8
- Formula:C24H38N2O3S
- Molecular Weight:434.64
IUPAC Name: 8-(3-((3,5-di-tert-butyl-4-hydroxyphenyl)thio)propyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
InChIKey: AQYBPUABOQSUHO-UHFFFAOYSA-N
SMILES: O=C1OC2(CN1)CCN(CC2)CCCSC3=CC(C(C)(C)C)=C(C(C(C)(C)C)=C3)O
Biological Activity: S12340 is a a inhibitor of the oxidative modification of low-density lipoprotein and shows protective effect on cardiac cells exposed to oxidative stress[1][2].
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S12340 | S12340 is a a inhibitor of the oxidative modification of low-density lipoprotein and shows protective effect on cardiac cells exposed to oxidative stress. | |||||||||||||||||||||
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References
- [1]. Breugnot C, et al. S 12340: a potent inhibitor of the oxidative modification of low-density lipoprotein in vitro and ex vivo in WHHL rabbits. J Pharmacol Exp Ther. 1994;269(2):515-520. [Content Brief]
- [2]. Iliou JP, et al. Protective effect of S12340 on cardiac cells exposed to oxidative stress. Eur J Pharmacol. 1993;248(3):263-272. [Content Brief]
