145915-60-2
145915-60-2
Chemical Structure
CGP-53353
Synonym(s): DAPH-7
- CAS No.: 145915-60-2
- Formula:C20H13F2N3O2
- Molecular Weight:365.33
IUPAC Name: 5,6-bis((4-fluorophenyl)amino)isoindoline-1,3-dione
InChIKey: RONQPWQYDRPRGG-UHFFFAOYSA-N
SMILES: O=C1NC(C2=C1C=C(NC3=CC=C(F)C=C3)C(NC4=CC=C(F)C=C4)=C2)=O
Biological Activity: CGP-53353 (DAPH-7) is an potent PKC inhibitor with IC50s of 0.41 μM and 3.8 μM for PKCβII and PKCβI, respectively. CGP-53353 can inhibit glucose-induced cell proliferation and DNA synthesis in AoSMC and A10 cells. CGP-53353 can be used for researching atherosclerosis of diabetic patients[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CGP-53353 | 98.87% | CGP-53353 (DAPH-7) is an potent PKC inhibitor with IC50s of 0.41 μM and 3.8 μM for PKCβII and PKCβI, respectively. CGP-53353 can inhibit glucose-induced cell proliferation and DNA synthesis in AoSMC and A10 cells. CGP-53353 can be used for researching atherosclerosis of diabetic patients. | ||||||||||||||||||||
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CGP-53353 (Standard) | ≥98% | CGP-53353 (Standard) is the analytical standard of CGP-53353 (HY-108600). This product is intended for research and analytical applications. CGP-53353 (DAPH-7) is an potent PKC inhibitor with IC50s of 0.41 μM and 3.8 μM for PKCβII and PKCβI, respectively. CGP-53353 can inhibit glucose-induced cell proliferation and DNA synthesis in AoSMC and A10 cells. CGP-53353 can be used for researching atherosclerosis of diabetic patients. | ||||||||||||||||||||
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References
Keywords
