2. Others Epigenetics TGF-beta/Smad Cell Cycle/DNA Damage
  3. Reference Standards PKC DNA/RNA Synthesis
  4. CGP-53353 (Standard)

CGP-53353 (Standard)  (Synonyms: DAPH-7 (Standard))

Cat. No.: HY-108600R
Handling Instructions Technical Support

CGP-53353 (Standard) is the analytical standard of CGP-53353 (HY-108600). This product is intended for research and analytical applications. CGP-53353 (DAPH-7) is an potent PKC inhibitor with IC50s of 0.41 μM and 3.8 μM for PKCβII and PKCβI, respectively. CGP-53353 can inhibit glucose-induced cell proliferation and DNA synthesis in AoSMC and A10 cells. CGP-53353 can be used for researching atherosclerosis of diabetic patients.

For research use only. We do not sell to patients.

CGP-53353 (Standard)

CGP-53353 (Standard) Chemical Structure

CAS No. : 145915-60-2

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Information

CGP-53353 (Standard) is the analytical standard of CGP-53353 (HY-108600). This product is intended for research and analytical applications. CGP-53353 (DAPH-7) is an potent PKC inhibitor with IC50s of 0.41 μM and 3.8 μM for PKCβII and PKCβI, respectively. CGP-53353 can inhibit glucose-induced cell proliferation and DNA synthesis in AoSMC and A10 cells. CGP-53353 can be used for researching atherosclerosis of diabetic patients.

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molecular Weight

365.33

Formula

C20H13F2N3O2
CAS No.
SMILES

O=C1NC(C2=C1C=C(NC3=CC=C(F)C=C3)C(NC4=CC=C(F)C=C4)=C2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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CGP-53353 (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CGP-53353 (Standard)145915-60-2DAPH-7 (Standard)Reference StandardsPKCDNA/RNA SynthesisProtein kinase CVSMCCell proliferationGlucoseDiabetesInhibitorinhibitorinhibit

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