1461658-58-1
1461658-58-1
Chemical Structure
CK2-IN-9
- CAS No.: 1461658-58-1
- Formula:C23H29N9O
- Molecular Weight:447.54
IUPAC Name: N-(5-((3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl)amino)-2-((2-(dimethylamino)ethyl)(methyl)amino)phenyl)acetamide
InChIKey: SRABOMKMQRYXIK-UHFFFAOYSA-N
SMILES: O=C(C)NC1=CC(NC2=NC3=C(C#N)C=NN3C(NC4CC4)=C2)=CC=C1N(CCN(C)C)C
Biological Activity: CK2-IN-9 is a potent and selective inhibitor of CK2 kinase with an IC50 of 3 nM. CK2-IN-9 reduces Wnt reporter activity with an IC50 of 75 nM. CK2-IN-9 has low exposure (AUC=0.36 μM/h) and high clearance (CL=65 mL/min/kg) properties in rat[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
CK2-IN-9 | CK2-IN-9 is a potent and selective inhibitor of CK2 kinase with an IC50 of 3 nM. CK2-IN-9 reduces Wnt reporter activity with an IC50 of 75 nM. CK2-IN-9 has low exposure (AUC=0.36 μM/h) and high clearance (CL=65 mL/min/kg) properties in rat. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
