148407-07-2
Chemical Structure
UDP-galacturonic acid trisodium
- CAS No.: 148407-07-2
- Formula:C15H19N2Na3O18P2
- Molecular Weight:646.23
IUPAC Name: sodium (2S,3R,4S,5R,6R)-6-(((((((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)oxidophosphoryl)oxy)oxidophosphoryl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate
InChIKey: XXXUNWUNTOMVIG-DSWQXYTCSA-K
SMILES: O[C@H]1[C@@H](C(O[Na])=O)O[C@H](OP(OP(OC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C=CC(NC3=O)=O)O2)(O[Na])=O)(O[Na])=O)[C@H](O)[C@H]1O
Biological Activity: UDP-galacturonic acid trisodium is a nucleotide sugar complex that serves as a cofactor for UDP-glucuronosyltransferases and a substrate for galacturonosyltransferases in bacterial surface polysaccharide and plant pectin biosynthesis. UDP-galacturonic acid trisodium is used in the study of plant development and bacterial pathogenic mechanisms[1][2][3][4][5][6][7].
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UDP-galacturonic acid trisodium | UDP-galacturonic acid trisodium is a nucleotide sugar complex that serves as a cofactor for UDP-glucuronosyltransferases and a substrate for galacturonosyltransferases in bacterial surface polysaccharide and plant pectin biosynthesis. UDP-galacturonic acid trisodium is used in the study of plant development and bacterial pathogenic mechanisms. | |||||||||||||||||||||
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References
- [1]. Neufeld EF. Enzymatic conversion of uridine diphosphate d-glucuronic acid to uridine diphosphate galacturonic acid, uridine diphosphate xylose, and uridine diphosphate arabinose1, 2. Journal of the American Chemical Society. 1958 Aug;80(16):4430-1.
- [2]. Gschaidmeier H, et al. Formation of mono- and diglucuronides and other glycosides of benzo(a)pyrene-3,6-quinol by V79 cell-expressed human phenol UDP-glucuronosyltransferases of the UGT1 gene complex. Biochemical pharmacology. 1995 May 26;49(11):1601-6.
- [3]. Frirdich E, et al. Characterization of Gla(KP), a UDP-galacturonic acid C4-epimerase from Klebsiella pneumoniae with extended substrate specificity. Journal of bacteriology. 2005 Jun;187(12):4104-15.
- [4]. Broach B, et al. Biosynthesis of UDP-glucuronic acid and UDP-galacturonic acid in Bacillus cereus subsp. cytotoxis NVH 391-98. The FEBS journal. 2012 Jan;279(1):100-12.
- [5]. Ohashi T, et al. Preparation of UDP-galacturonic acid using UDP-sugar pyrophosphorylase. Analytical biochemistry. 2006 May 15;352(2):182-7.
- [6]. Gu X, et al. The biosynthesis of UDP-galacturonic acid in plants. Functional cloning and characterization of Arabidopsis UDP-D-glucuronic acid 4-epimerase. Plant Physiol. 2004 Dec;136(4):4256-64. [Content Brief]
- [7]. Geserick C, et al. UDP-sugar pyrophosphorylase is essential for arabinose and xylose recycling, and is required during vegetative and reproductive growth in Arabidopsis. The Plant journal : for cell and molecular biology. 2013 Apr;74(2):239-47.
