149760-98-5
Chemical Structure
AS1134900
- CAS No.: 149760-98-5
- Formula:C25H22N8S
- Molecular Weight:466.56
IUPAC Name: 2-(2-(1H-tetrazol-5-yl)phenyl)-6-((7-methyl-2-propyl-4H-imidazo[4,5-b]pyridin-4-yl)methyl)benzo[d]thiazole
InChIKey: LGDMZWWVVLGYPR-UHFFFAOYSA-N
SMILES: CCCC1=NC2=C(C)C=CN(CC3=CC=C4N=C(C5=CC=CC=C5C6=NN=NN6)SC4=C3)C2=N1
Biological Activity: AS1134900 is a highly selective uncompetitive allosteric inhibitor of NADP+-dependent malic enzyme 1 (ME1) with an IC50 of 0.73 μM. AS1134900 can be used in the study of cancer[1].
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AS1134900 | 98.87% | AS1134900 is a highly selective uncompetitive allosteric inhibitor of NADP+-dependent malic enzyme 1 (ME1) with an IC50 of 0.73 μM. AS1134900 can be used in the study of cancer. | ||||||||||||||||||||
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Keywords