15883-20-2
15883-20-2
Chemical Structure
N-Desbutyl Bupivacaine
Synonym(s): Desbutylbupivacaine
- CAS No.: 15883-20-2
- Formula:C14H20N2O
- Molecular Weight:232.32
IUPAC Name: N-(2,6-dimethylphenyl)piperidine-2-carboxamide
InChIKey: SILRCGDPZGQJOQ-UHFFFAOYSA-N
SMILES: CC1=CC=CC(C)=C1NC(C2CCCCN2)=O
Biological Activity: N-Desbutyl Bupivacaine (compound 100) is a metabolite of Bupivacaine (HY-B0405), an NMDA receptor inhibitor and SCN5A antagonist[1][2].
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N-Desbutyl Bupivacaine | N-Desbutyl Bupivacaine (compound 100) is a metabolite of Bupivacaine (HY-B0405), an NMDA receptor inhibitor and SCN5A antagonist. | |||||||||||||||||||||
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N-Desbutyl bupivacaine-d6 | N-Desbutyl bupivacaine-d6 (Desbutylbupivacaine-d6) is the deuterium labeled N-Desbutyl Bupivacaine (HY-W045132). N-Desbutyl Bupivacaine (compound 100) is a metabolite of Bupivacaine (HY-B0405), an NMDA receptor inhibitor and SCN5A antagonist. | |||||||||||||||||||||
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References
- [1]. Meaghan A Paganelli, et al. Actions of Bupivacaine, a widely used local anesthetic, on NMDA receptor responses. J Neurosci. 2015 Jan 14;35(2):831-42. [Content Brief]
- [2]. Alexander P Schwoerer, et al. A Comparative Analysis of Bupivacaine and Ropivacaine Effects on Human Cardiac SCN5A Channels. Anesth Analg. 2015 Jun;120(6):1226-34. [Content Brief]
