16085-74-8
Chemical Structure
TAP-05
- CAS No.: 16085-74-8
- Formula:C15H11N5O2S
- Molecular Weight:325.35
InChIKey: QQIIECCQLAXVNP-RQZCQDPDSA-N
SMILES: O=[N+](C1=CC(C2=CSC(N/N=C/C3=NC=CC=C3)=N2)=CC=C1)[O-]
Biological Activity: TAP-05 is a thiazole small molecule with inhibitory activity against parasites. TAP-05 inhibits the growth of Toxoplasma gondii and Leishmania infantum. TAP-05 can be used for research on toxoplasmosis and visceral leishmaniasis[1][2].
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TAP-05 | TAP-05 is a thiazole small molecule with inhibitory activity against parasites. TAP-05 inhibits the growth of Toxoplasma gondii and Leishmania infantum. TAP-05 can be used for research on toxoplasmosis and visceral leishmaniasis. | |||||||||||||||||||||
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References
- [1]. Dias IO, et al. Highly Selective Thiazole Derivatives as Promising Anti-Toxoplasma gondii Agents. ACS Omega. 2026 Sep 24;11(39):59807-59814. [Content Brief]
- [2]. de Oliveira VVG, et al. Study of in vitro biological activity of thiazoles on Leishmania (Leishmania) infantum. Journal of global antimicrobial resistance. 2020 Sep;22:414-421. [Content Brief]