1616359-00-2
1616359-00-2
Chemical Structure
SEL24-B489
- CAS No.: 1616359-00-2
- Formula:C15H18Br2N4O2
- Molecular Weight:446.14
IUPAC Name: 5,6-dibromo-1-isopropyl-4-nitro-2-(piperidin-4-yl)-1H-benzo[d]imidazole
InChIKey: UOUBCIJIWDLRGM-UHFFFAOYSA-N
SMILES: CC(N1C(C2CCNCC2)=NC3=C([N+]([O-])=O)C(Br)=C(Br)C=C31)C
Biological Activity:
SEL24-B489 is a potent, type I, orally active, dual PIM and FLT3-ITD inhibitor, with Kd values of 2 nM for PIM1, 2 nM for PIM2 and 3 nM for PIM3, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
SEL24-B489 | 99.02% | SEL24-B489 is a potent, type I, orally active, dual PIM and FLT3-ITD inhibitor, with Kd values of 2 nM for PIM1, 2 nM for PIM2 and 3 nM for PIM3, respectively. |
||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.50
HY-W103105R 29676 -
Similarity Score 0.48
HY-D01364-Nitro-7-piperazinobenzofurazan -
Similarity Score 0.48
![1-(Piperidin-4-yl)-1H-imidazo[4,5-b]pyridin-2(3H)-one Hydrochloride Chemical Structure](//file.medchemexpress.com/product_pic/hy-32694.gif)
HY-326941-(Piperidin-4-yl)-1H-imidazo[4,5-b]pyridin-2(3H)-one Hydrochloride -
Similarity Score 0.47
HY-119467MDK0734 -
Similarity Score 0.47
HY-1371616-Nitroquipazine -
Similarity Score 0.47
HY-135906CK2/ERK8-IN-1 -
Similarity Score 0.47
HY-W998276CRBN ligand-796 -
Similarity Score 0.46
HY-W382038E3 ligase Ligand 32 -
Similarity Score 0.46
HY-45512E3 ligase Ligand 63 -
Explore the MedChemAI to find more analogs
![1-(Piperidin-4-yl)-1H-imidazo[4,5-b]pyridin-2(3H)-one Hydrochloride Chemical Structure](http://file.medchemexpress.com/product_pic/hy-32694.gif)
