161973-10-0
Chemical Structure
Esomeprazole magnesium
Synonym(s): (S)-Omeprazole magnesium; (-)-Omeprazole magnesium
- CAS No.: 161973-10-0
- Formula:C34H36MgN6O6S2
- Molecular Weight:713.12
InChIKey: KWORUUGOSLYAGD-UHFFFAOYSA-N
SMILES: CC1=C(N=CC(C)=C1OC)CS2=O[Mg+2]3([N](C4=CC=C(OC)C=C4[N-]5)=C5S(CC(N=CC(C)=C6OC)=C6C)=O3)[N]7=C2[N-]C8=CC(OC)=CC=C78
Biological Activity: Esomeprazole magnesium ((S)-Omeprazole magnesium) is a potent and orally active H+, K+-ATPase inhibitor. Esomeprazole magnesium has the potential for upper intestinal disorders and gastroesophageal reflux disease research[1][2]. Esomeprazole magnesium acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H+-ATPases[4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Esomeprazole magnesium | 99.92% | Esomeprazole magnesium ((S)-Omeprazole magnesium) is a potent and orally active H+, K+-ATPase inhibitor. Esomeprazole magnesium has the potential for upper intestinal disorders and gastroesophageal reflux disease research. Esomeprazole magnesium acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H+-ATPases. | ||||||||||||||||||||
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- [1]. Timothy R Koch, et al. Effect of the H, K-ATPase inhibitor, esomeprazole magnesium, on gut total antioxidant capacity in mice. J Nutr Biochem. 2004 Sep;15(9):522-6. [Content Brief]
- [2]. Pankaj Kumar, et al. Preparation and characterization of pH-sensitive methyl methacrylate-g-starch/hydroxypropylated starch hydrogels: in vitro and in vivo study on release of esomeprazole magnesium. Drug Deliv Transl Res. 2015 Jun;5(3):243-56. [Content Brief]
- [4]. Huarui Zhang, et al. Advances in the discovery of exosome inhibitors in cancer. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1322-1330. [Content Brief]
Keywords
