1627494-13-6
1627494-13-6
Chemical Structure
AZD8186
- CAS No.: 1627494-13-6
- Formula:C24H25F2N3O4
- Molecular Weight:457.47
IUPAC Name: (R)-8-(1-((3,5-difluorophenyl)amino)ethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide
InChIKey: LMJFJIDLEAWOQJ-CQSZACIVSA-N
SMILES: O=C(C1=CC([C@H](NC2=CC(F)=CC(F)=C2)C)=C3C(C(C=C(N4CCOCC4)O3)=O)=C1)N(C)C
Biological Activity: AZD8186 is a PI3K inhibitor, which potently inhibits PI3Kβ (IC50=4 nM) and PI3Kδ (IC5050=12 nM) with selectivity over PI3Kα (IC50=35 nM) and PI3Kγ (IC50=675 nM).
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AZD8186 | 99.98% | AZD8186 is a PI3K inhibitor, which potently inhibits PI3Kβ (IC50=4 nM) and PI3Kδ (IC5050=12 nM) with selectivity over PI3Kα (IC50=35 nM) and PI3Kγ (IC50=675 nM). | ||||||||||||||||||||
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