1628690-73-2
1628690-73-2
Chemical Structure
LY3202626
- CAS No.: 1628690-73-2
- Formula:C22H20F2N8O2S
- Molecular Weight:498.51
IUPAC Name: N-(3-((4aR,7aS)-2-amino-6-(5-fluoropyrimidin-2-yl)-4a,5,6,7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7a(4H)-yl)-4-fluorophenyl)-5-methoxypyrazine-2-carboxamide
InChIKey: VQSRKMNBWMHJKY-YTEVENLXSA-N
SMILES: O=C(NC1=CC=C(C([C@@]23N=C(SC[C@@]2(CN(C3)C4=NC=C(C=N4)F)[H])N)=C1)F)C5=NC=C(N=C5)OC
Biological Activity: LY3202626 is a CNS penetrant BACE inhibitor with IC50s of 0.615 nM and 0.871 nM against BACE1 and BACE2, respectively[1].
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LY3202626 | LY3202626 is a CNS penetrant BACE inhibitor with IC50s of 0.615 nM and 0.871 nM against BACE1 and BACE2, respectively. | |||||||||||||||||||||
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