163059-33-4
Chemical Structure
(R)-Thionisoxetine
Synonym(s): LY-368975
- CAS No.: 163059-33-4
- Formula:C17H21NOS
- Molecular Weight:287.42
IUPAC Name: (R)-N-methyl-3-(2-(methylthio)phenoxy)-3-phenylpropan-1-amine
InChIKey: NDVZIUGCCMZHLG-OAHLLOKOSA-N
SMILES: CSC1=CC=CC=C1O[C@@H](C2=CC=CC=C2)CCNC
Biological Activity: (R)-Thionisoxetine is a potent and selective inhibitor of central and peripheral norepinephrine (NE) uptake. (R)-thionisoxetine prevented hypothalamic NE depletion by 6-hydroxydopamine with an ED50 of 0.21 mg/kg. (R)-Thionisoxetine can be used for the research of a variety of diseases including depression and urinary incontinence[1].
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(R)-Thionisoxetine | (R)-Thionisoxetine is a potent and selective inhibitor of central and peripheral norepinephrine (NE) uptake. (R)-thionisoxetine prevented hypothalamic NE depletion by 6-hydroxydopamine with an ED50 of 0.21 mg/kg. (R)-Thionisoxetine can be used for the research of a variety of diseases including depression and urinary incontinence. | |||||||||||||||||||||
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Keywords
