1643809-54-4
1643809-54-4
Chemical Structure
AZD6642
- CAS. Nr.: 1643809-54-4
- Formula:C24H27N5O3
- Molecular Weight:433.50
IUPAC Name: (R)-5-(2-(4-(5-aminopyrazin-2-yl)phenyl)tetrahydrofuran-2-yl)-N-(2-hydroxy-2-methylpropyl)picolinamide
InChIKey: SJGLLGFHNAVMQI-XMMPIXPASA-N
SMILES: CC(C)(O)CNC(C1=NC=C([C@]2(C3=CC=C(C4=NC=C(N)N=C4)C=C3)CCCO2)C=C1)=O
Biological Activity: AZD6642 is a 5-lipoxygenase activating protein (FLAP) inhibitor. AZD6642 can effectively inhibit the production of LTB4. AZD6642 exhibits high oral bioavailability in rats and dogs. AZD6642 can be used in the research of inflammatory diseases[1].
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AZD6642 | AZD6642 is a 5-lipoxygenase activating protein (FLAP) inhibitor. AZD6642 can effectively inhibit the production of LTB4. AZD6642 exhibits high oral bioavailability in rats and dogs. AZD6642 can be used in the research of inflammatory diseases. | |||||||||||||||||||||
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References
Keywords
