167498-29-5
167498-29-5
Chemical Structure
Z-FY-CHO
Synonym(s): Z-Phe-Tyr-CHO
- CAS No.: 167498-29-5
- Formula:C26H26N2O5
- Molecular Weight:446.50
IUPAC Name: benzyl ((S)-1-(((S)-1-(4-hydroxyphenyl)-3-oxopropan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate
InChIKey: QVDJMLQSYRSZKC-UPVQGACJSA-N
SMILES: O=C(OCC1=CC=CC=C1)N[C@@H](CC2=CC=CC=C2)C(N[C@H](C=O)CC3=CC=C(O)C=C3)=O
Biological Activity: Z-FY-CHO (Z-Phe-Tyr-CHO) is a potent and specific cathepsin L (CTSL) inhibitor[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Z-FY-CHO | 95.0% | Z-FY-CHO (Z-Phe-Tyr-CHO) is a potent and specific cathepsin L (CTSL) inhibitor. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.76
HY-115733Cathepsin L-IN-2 -
Similarity Score 0.76
HY-141867Z-FF-FMK -
Similarity Score 0.75
HY-114437Fusion Inhibitory Peptide -
Similarity Score 0.74
HY-P4306Z-Phe-Phe-Diazomethylketone -
Similarity Score 0.74
HY-P5042Cbz-Tyr-Ala-OH -
Similarity Score 0.73
HY-138208Z-Phe-Tyr(tBu)-diazomethylketone -
Similarity Score 0.73
HY-W046406Z-Phe-Ala-OH -
Similarity Score 0.72
HY-W317373Z-Phe-gly-oh -
Similarity Score 0.72
HY-P0109(S,S)-Z-FA-FMK -
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References
- [1]. Lingyun Li, et al. Activated cathepsin L is associated with the switch from autophagy to apoptotic death of SH-SY5Y cells exposed to 6-hydroxydopamine. Biochem Biophys Res Commun. 2016 Feb 12;470(3):579-585. [Content Brief]
- [2]. Qing-qing Zhang, et al. Cathepsin L suppression increases the radiosensitivity of human glioma U251 cells via G2/M cell cycle arrest and DNA damage. Acta Pharmacol Sin. 2015 Sep;36(9):1113-25. [Content Brief]
