17157-12-9
17157-12-9
Chemical Structure
Isoquinoline-d7
- CAS No.: 17157-12-9
- Formula:C9D7N
- Molecular Weight:136.21
IUPAC Name: isoquinoline-d7
InChIKey: AWJUIBRHMBBTKR-GSNKEKJESA-N
SMILES: [2H]C1=C([2H])C([2H])=C([2H])C2=C1C([2H])=C([2H])N=C2[2H]
Biological Activity: Isoquinoline-d7 is the deuterium labeled Isoquinoline[1]. Isoquinoline is an analog of pyridine. Isoquinoline structural-based alkaloids, such as tropoloisoquinoline, phthalideisoquinoline, and naphthylisoquinoline has anti-cancer activities[2].
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Isoquinoline-d7 | 99.33% | Isoquinoline-d7 is the deuterium labeled Isoquinoline. Isoquinoline is an analog of pyridine. Isoquinoline structural-based alkaloids, such as tropoloisoquinoline, phthalideisoquinoline, and naphthylisoquinoline has anti-cancer activities. | ||||||||||||||||||||
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Isoquinoline (Standard) | ≥98% | Isoquinoline (Standard) is the analytical standard of Isoquinoline. This product is intended for research and analytical applications. Isoquinoline is an analog of pyridine. Isoquinoline structural-based alkaloids, such as tropoloisoquinoline, phthalideisoquinoline, and naphthylisoquinoline has anti-cancer activities. | ||||||||||||||||||||
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Isoquinoline-15N | Isoquinoline-15N is the 15N-labeled Isoquinoline (HY-W012732). Isoquinoline is an analog of pyridine. Isoquinoline-based alkaloids, such as p-tolyl bisisoquinoline, phthaloyl isoquinoline, and naphthyl isoquinoline, exhibit anticancer activity. Berberine, an isoquinoline alkaloid, exerts anti-inflammatory effects in diabetic mice by downregulating the gene expression ratios of pro-/anti-inflammatory and Th1/Th2 cytokines. Additionally, some isoquinoline-based compounds also possess antidepressant, antibacterial, antimalarial, and anti-HIV activities. | |||||||||||||||||||||
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Isoquinoline | 99.66% | Isoquinoline is an analog of pyridine. Isoquinoline-based alkaloids, such as p-tolyl bisisoquinoline, phthaloyl isoquinoline, and naphthyl isoquinoline, exhibit anticancer activity. Berberine, an isoquinoline alkaloid, exerts anti-inflammatory effects in diabetic mice by downregulating the gene expression ratios of pro-/anti-inflammatory and Th1/Th2 cytokines. Additionally, some isoquinoline-based compounds also possess antidepressant, antibacterial, antimalarial, and anti-HIV activities. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.88
HY-W7102473-Hydroxyquinoline-d6 -
Similarity Score 0.86
HY-W007608S1-Iodonaphthalene-d7 -
Similarity Score 0.86
HY-124451S2-Chloronaphthalene-d7 -
Similarity Score 0.86
HY-Y0110S12-Naphthol-d7 -
Similarity Score 0.86
HY-W007537S2-Bromonaphthalene-d7 -
Similarity Score 0.86
HY-Y1119S1-Bromonaphthalene-d7 -
Similarity Score 0.86
HY-Y1309S11-Naphthol-d7 -
Similarity Score 0.84
HY-690557-Bromoisoquinoline -
Similarity Score 0.84
HY-690926-Bromoisoquinoline -
Explore the MedChemAI to find more analogs
References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Zhi-Xing Qing, et al. Anticancer and Reversing Multidrug Resistance Activities of Natural Isoquinoline Alkaloids and Their Structure-activity Relationship. Curr Med Chem [Content Brief]
