177530-93-7
177530-93-7
Chemical Structure
(Rac)-Efavirenz
Synonym(s): (Rac)-DMP 266; (Rac)-EFV; (Rac)-L-743726
- CAS No.: 177530-93-7
- Formula:C14H9ClF3NO2
- Molecular Weight:315.67
IUPAC Name: 6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one
InChIKey: XPOQHMRABVBWPR-UHFFFAOYSA-N
SMILES: O=C1OC(C2=CC(Cl)=CC=C2N1)(C(F)(F)F)C#CC3CC3
Biological Activity: (Rac)-Efavirenz is the isomer of Efavirenz (HY-10572). Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture[1].
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(Rac)-Efavirenz | (Rac)-Efavirenz is the isomer of Efavirenz (HY-10572). Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture. | |||||||||||||||||||||
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(Rac)-Efavirenz (Standard) | ≥98% | (Rac)-Efavirenz (Standard) is the analytical standard of (Rac)-Efavirenz. This product is intended for research and analytical applications. (Rac)-Efavirenz is the isomer of Efavirenz (HY-10572). Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture. | ||||||||||||||||||||
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(Rac)-Efavirenz-d5 | (Rac)-Efavirenz-d5 is deuterium labeled (Rac)-Efavirenz. (Rac)-Efavirenz-d5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | |||||||||||||||||||||
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References
