1788063-52-4
1788063-52-4
Chemical Structure
GDC-0310
- CAS No.: 1788063-52-4
- Formula:C25H29Cl2FN2O4S
- Molecular Weight:543.48
IUPAC Name: (S)-5-cyclopropyl-4-((1-(1-(3,5-dichlorophenyl)ethyl)piperidin-4-yl)methoxy)-2-fluoro-N-(methylsulfonyl)benzamide
InChIKey: SXOAHIZWCZOILH-HNNXBMFYSA-N
SMILES: O=C(NS(=O)(C)=O)C1=CC(C2CC2)=C(OCC3CCN([C@H](C4=CC(Cl)=CC(Cl)=C4)C)CC3)C=C1F
Biological Activity: GDC-0310 is a selective acyl-sulfonamide Nav1.7 inhibitor, with an IC50 of 0.6 nM for hNav1.7[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GDC-0310 | 98.84% | GDC-0310 is a selective acyl-sulfonamide Nav1.7 inhibitor, with an IC50 of 0.6 nM for hNav1.7. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.73
HY-131870GX-201 -
Similarity Score 0.64
HY-102998Nav1.7-IN-6 -
Similarity Score 0.55
HY-119934NaV1.7 inhibitor-1 -
Similarity Score 0.53
HY-114237GDC-0276 -
Similarity Score 0.49
HY-13985Nav1.7 inhibitor -
Similarity Score 0.46
HY-101343RS 39604 -
Similarity Score 0.46
HY-16729Relenopride -
Similarity Score 0.45
HY-16729ARelenopride hydrochloride -
Similarity Score 0.45
HY-147056PKRA83 -
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