1798787-27-5
1798787-27-5
Chemical Structure
BIIB068
- CAS No.: 1798787-27-5
- Formula:C23H29N7O2
- Molecular Weight:435.52
IUPAC Name: 3-isopropoxy-N-(2-methyl-4-(2-((1-methyl-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)benzyl)azetidine-1-carboxamide
InChIKey: BMWMKGNVAMXXCH-UHFFFAOYSA-N
SMILES: O=C(N1CC(OC(C)C)C1)NCC2=CC=C(C3=NC(NC4=CN(C)N=C4)=NC=C3)C=C2C
Biological Activity: BIIB068 is a potent, selective, reversible and orally active BTK inhibitor with an IC50 of 1 nM and a Kd of 0.3 nM. BIIB068 shows more >400-fold selective for BTK than other kinases. BIIB068 has the potential for autoimmune diseases research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BIIB068 | 98.35% | BIIB068 is a potent, selective, reversible and orally active BTK inhibitor with an IC50 of 1 nM and a Kd of 0.3 nM. BIIB068 shows more >400-fold selective for BTK than other kinases. BIIB068 has the potential for autoimmune diseases research. | ||||||||||||||||||||
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References
Keywords
