182485-36-5

TPMPA Chemical Structure
182485-36-5

Chemical Structure

TPMPA

  • CAS No.: 182485-36-5
  • Formula:C6H12NO2P
  • Molecular Weight:161.14

IUPAC Name: methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid

InChIKey: MFUKVPOVVKKLRQ-UHFFFAOYSA-N

SMILES: O=P(C1=CCNCC1)(C)O

Biological Activity: TPMPA, a hybrid of isoguvacine and 3-APMPA, is the first selective antagonist for a GABAC receptor (KB = 2.1 μM), but not to interact with GABAA (KB = 320 μM) or GABAB receptors (EC50 = 500 μM). TPMPA has the potential for the research of suppressing orientation selectivity in ganglion cells[1][2][3].

Cat. No. Product Name Purity Description Pricing
HY-101359 		TPMPA 99.9% TPMPA, a hybrid of isoguvacine and 3-APMPA, is the first selective antagonist for a GABAC receptor (KB = 2.1 μM), but not to interact with GABAA (KB = 320 μM) or GABAB receptors (EC50 = 500 μM). TPMPA has the potential for the research of suppressing orientation selectivity in ganglion cells.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

References

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