1835705-55-9
Chemical Structure
(S,R,S)-AHPC-C6-PEG3-C4-Cl
Synonym(s): VH032-C6-PEG3-C4-Cl; VHL Ligand-Linker Conjugates 12; E3 ligase Ligand-Linker Conjugates 8
- CAS No.: 1835705-55-9
- Formula:C38H59ClN4O7S
- Molecular Weight:751.42
IUPAC Name: (2S,4R)-1-((S)-2-(tert-butyl)-22-chloro-4-oxo-10,13,16-trioxa-3-azadocosanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
InChIKey: MLRLOIWXHCPWFF-MEEYNGGZSA-N
SMILES: O=C([C@H]1N(C([C@H](C(C)(C)C)NC(CCCCCOCCOCCOCCCCCCCl)=O)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2
Biological Activity: (S,R,S)-AHPC-C6-PEG3-C4-Cl (VH032-C6-PEG3-C4-Cl) is a conjugate of ligands for E3 and 20-atom-length linker. The connector of linker is Halogen group. (S,R,S)-AHPC-C6-PEG3-C4-Cl incorporates the (S,R,S)-AHPC based VHL ligand and an alkyl/ether-based linker. (S,R,S)-AHPC-C6-PEG3-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
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(S,R,S)-AHPC-C6-PEG3-C4-Cl | 97.01% | (S,R,S)-AHPC-C6-PEG3-C4-Cl (VH032-C6-PEG3-C4-Cl) is a conjugate of ligands for E3 and 20-atom-length linker. The connector of linker is Halogen group. (S,R,S)-AHPC-C6-PEG3-C4-Cl incorporates the (S,R,S)-AHPC based VHL ligand and an alkyl/ether-based linker. (S,R,S)-AHPC-C6-PEG3-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays. | ||||||||||||||||||||
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(S,R,S)-AHPC-C6-PEG3-C4-Cl (Standard) | ≥98% | (S,R,S)-AHPC-C6-PEG3-C4-Cl (Standard) is the analytical standard of (S,R,S)-AHPC-C6-PEG3-C4-Cl (HY-103605). This product is intended for research and analytical applications. (S,R,S)-AHPC-C6-PEG3-C4-Cl (VH032-C6-PEG3-C4-Cl) is a conjugate of ligands for E3 and 20-atom-length linker. The connector of linker is Halogen group. (S,R,S)-AHPC-C6-PEG3-C4-Cl incorporates the (S,R,S)-AHPC based VHL ligand and an alkyl/ether-based linker. (S,R,S)-AHPC-C6-PEG3-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays. | ||||||||||||||||||||
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