185351-19-3
Chemical Structure
NQTrp
- CAS No.: 185351-19-3
- Formula:C21H16N2O4
- Molecular Weight:360.36
IUPAC Name: (1,4-dioxo-1,4-dihydronaphthalen-2-yl)-L-tryptophan
InChIKey: DZZUYZXINNHEGM-SFHVURJKSA-N
SMILES: O=C(O)[C@H](CC1=CNC2=CC=CC=C12)NC(C3=O)=CC(C4=C3C=CC=C4)=O
Biological Activity: NQTrp, an aromatic naphthoquinone-tryptophan hybrid molecule, an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects. NQTrp inhibits the in vitro aggregation of hexapeptide (41GCWMLY46 within the N-terminus of γD-crystallin) as well as full-length γD-crystallin[1].
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NQTrp | 98.37% | NQTrp, an aromatic naphthoquinone-tryptophan hybrid molecule, an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects. NQTrp inhibits the in vitro aggregation of hexapeptide (41GCWMLY46 within the N-terminus of γD-crystallin) as well as full-length γD-crystallin. | ||||||||||||||||||||
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Keywords