185351-19-3
185351-19-3
Chemical Structure
NQTrp
- CAS No.: 185351-19-3
- Formula:C21H16N2O4
- Molecular Weight:360.36
IUPAC Name: (1,4-dioxo-1,4-dihydronaphthalen-2-yl)-L-tryptophan
InChIKey: DZZUYZXINNHEGM-SFHVURJKSA-N
SMILES: O=C(O)[C@H](CC1=CNC2=CC=CC=C12)NC(C3=O)=CC(C4=C3C=CC=C4)=O
Biological Activity: NQTrp, an aromatic naphthoquinone-tryptophan hybrid molecule, an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects. NQTrp inhibits the in vitro aggregation of hexapeptide (41GCWMLY46 within the N-terminus of γD-crystallin) as well as full-length γD-crystallin[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NQTrp | 98.37% | NQTrp, an aromatic naphthoquinone-tryptophan hybrid molecule, an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects. NQTrp inhibits the in vitro aggregation of hexapeptide (41GCWMLY46 within the N-terminus of γD-crystallin) as well as full-length γD-crystallin. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.80
HY-138643Cl-NQTrp -
Similarity Score 0.66
HY-13642A(Rac)-RG108 -
Similarity Score 0.66
HY-13642GRG108 (GMP) -
Similarity Score 0.62
HY-138815(S)-N-(1H-Indole-3-acetyl)tryptophan -
Similarity Score 0.61
HY-W009121Cbz-D-Trp-OH -
Similarity Score 0.61
HY-W011197Cbz-L-Trp-OH -
Similarity Score 0.61
HY-W097167N-Cbz-DL-tryptophan -
Similarity Score 0.61
HY-W092109RH-Phe-Trp-OH (Standard) -
Similarity Score 0.59
HY-121278Benzotript -
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