1914772-75-0
Chemical Structure
CHI3L1-IN-6
- CAS No.: 1914772-75-0
- Formula:C14H16ClN3O
- Molecular Weight:277.75
InChIKey: VGNLXRLWPFDOMT-UHFFFAOYSA-N
SMILES: ClC1=CC2=C(C=C1)CC(NCCC3=NOC(C)=N3)C2
Biological Activity: CHI3L1-IN-6 (Compound 9e) is a CHI3L1 inhibitor with a Kd of 19.11 μM for hCHI3L1. CHI3L1-IN-6 blocks CHI3L1-Galectin-3 interaction. CHI3L1-IN-6 reduces STAT3 signaling. CHI3L1-IN-6 exhibits anti-cancer activity against glioblastoma[1].
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CHI3L1-IN-6 | CHI3L1-IN-6 (Compound 9e) is a CHI3L1 inhibitor with a Kd of 19.11 μM for hCHI3L1. CHI3L1-IN-6 blocks CHI3L1-Galectin-3 interaction. CHI3L1-IN-6 reduces STAT3 signaling. CHI3L1-IN-6 exhibits anti-cancer activity against glioblastoma. | |||||||||||||||||||||
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Keywords