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Referencia número: HY-180937

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CHI3L1-IN-6

CHI3L1-IN-6 (Compound 9e) is a CHI3L1 inhibitor with a K_d of 19.11 μM for hCHI3L1. CHI3L1-IN-6 blocks CHI3L1-Galectin-3 interaction. CHI3L1-IN-6 reduces STAT3 signaling. CHI3L1-IN-6 exhibits anti-cancer activity against glioblastoma.

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No. CAS: 1914772-75-0
Fòrmula: C₁₄H₁₆ClN₃O
Peso molecular:277.75

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

CHI3L1-IN-6 Chemical Structure

No. CAS: 1914772-75-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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^[1]

STAT3

Galectin-3

Ver todos los productos específicos de isoformas STAT :

Ver todos los productos específicos de isoformas Galectin :

Chemical Information

No. CAS 1914772-75-0
Peso molecular 277.75
Fòrmula C₁₄H₁₆ClN₃O
SMILES

ClC1=CC2=C(C=C1)CC(NCCC3=NOC(C)=N3)C2
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

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Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Kaur B, et al. Structure-Guided Discovery of CHI3L1 Inhibitors from Ultralarge Chemical Spaces for Glioblastoma Therapy. bioRxiv [Preprint]. 2025 Aug 12:2025.08.09.669500. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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CHI3L1-IN-6

Ver todos los productos específicos de isoformas STAT

Ver todos los productos específicos de isoformas Galectin

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