200134-22-1
Chemical Structure
INH14
- CAS No.: 200134-22-1
- Formula:C15H16N2O
- Molecular Weight:240.30
IUPAC Name: 1-(4-ethylphenyl)-3-phenylurea
InChIKey: CPCZNJSFVOOZOG-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=CC=C1)NC2=CC=C(CC)C=C2
Biological Activity: INH14 is a cell permeable inhibitor of IKKα/IKKβ, with IC50s of 8.97 and 3.59 μM, respectively. INH14 inhibits the IKKα/β-dependent TLR inflammatory response. INH14 also inhibits downstream of TAK1/TAB1 and NF-kB pathways. Anti-inflammatory and anti-cancer activity[1].
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INH14 | 98.0% | INH14 is a cell permeable inhibitor of IKKα/IKKβ, with IC50s of 8.97 and 3.59 μM, respectively. INH14 inhibits the IKKα/β-dependent TLR inflammatory response. INH14 also inhibits downstream of TAK1/TAB1 and NF-kB pathways. Anti-inflammatory and anti-cancer activity. | ||||||||||||||||||||
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Keywords