200484-11-3
200484-11-3
Chemical Structure
CHS-828
Synonym(s): GMX1778
- CAS No.: 200484-11-3
- Formula:C19H22ClN5O
- Molecular Weight:371.86
InChIKey: BOIPLTNGIAPDBY-UHFFFAOYSA-N
SMILES: N#CN/C(NCCCCCCOC1=CC=C(C=C1)Cl)=N\C2=CC=NC=C2
Biological Activity: CHS-828 (GMX1778) is a competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), with an IC50 less than 25 nM. CHS-828 (GMX1778) exerts a cytotoxic effect by decreasing the cellular level of NAD+ and exhibits a potent anticancer activity[1].
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CHS-828 | 99.28% | CHS-828 (GMX1778) is a competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), with an IC50 less than 25 nM. CHS-828 (GMX1778) exerts a cytotoxic effect by decreasing the cellular level of NAD+ and exhibits a potent anticancer activity. | ||||||||||||||||||||
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CHS-828 (Standard) | ≥98% | CHS-828 (Standard) is the analytical standard of CHS-828. This product is intended for research and analytical applications. CHS-828 (GMX1778) is a competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), with an IC50 less than 25 nM. CHS-828 (GMX1778) exerts a cytotoxic effect by decreasing the cellular level of NAD+ and exhibits a potent anticancer activity. | ||||||||||||||||||||
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References
Keywords
