2012601-57-7
2012601-57-7
Chemical Structure
N-Desethyl Sunitinib-d4 TFA
Synonym(s): SU-12662-d4 TFA
- CAS No.: 2012601-57-7
- Formula:C22H20D4F4N4O4
- Molecular Weight:488.47
InChIKey: CDMPEGQUFONIGN-FFZXVIRXSA-N
SMILES: FC(F)(C(O)=O)F.O=C1NC2=CC=C(F)C=C2/C1=C/C3=C(C)C(C(NCCNC([2H])C([2H])([2H])[2H])=O)=C(C)N3
Biological Activity: N-Desethyl Sunitinib-d4 (SU-12662-d4) TFA is deuterium-labeled N-Desethyl Sunitinib (HY-10873)[1].
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N-Desethyl Sunitinib-d4 TFA | N-Desethyl Sunitinib-d4 (SU-12662-d4) TFA is deuterium-labeled N-Desethyl Sunitinib (HY-10873). | |||||||||||||||||||||
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N-Desethyl Sunitinib (Standard) | ≥98% | N-Desethyl Sunitinib (Standard) is the analytical standard of N-Desethyl Sunitinib. This product is intended for research and analytical applications. N-Desethyl Sunitinib (SU-12662) is a metabolite of sunitinib. Sunitinib is a potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor with Ki values of 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT, respectively. | ||||||||||||||||||||
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N-Desethyl Sunitinib-d5 | 99.9% | N-Desethyl Sunitinib-d5 is the deuterium labeled N-Desethyl Sunitinib. N-Desethyl Sunitinib (SU-12662) is a metabolite of sunitinib. Sunitinib is a potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor with Ki values of 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT, respectively. | ||||||||||||||||||||
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N-Desethyl Sunitinib-d5 hydrochloride | N-Desethyl Sunitinib-d5 (hydrochloride) is a deuterated labeled N-Desethyl Sunitinib. N-Desethyl Sunitinib (SU-12662) is a metabolite of sunitinib. Sunitinib is a potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor with Ki values of 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT, respectively. | |||||||||||||||||||||
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N-Desethyl Sunitinib | 99.81% | N-Desethyl Sunitinib (SU-12662) is a metabolite of Sunitinib (HY-10255A). N-Desethyl Sunitinib serves as a good transport substrate for human ABCB1, ABCG2 and murine ABCG2. | ||||||||||||||||||||
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References
