2064121-65-7
Chemical Structure
Asundexian
Synonym(s): BAY-2433334
- CAS No.: 2064121-65-7
- Formula:C26H21ClF4N6O4
- Molecular Weight:592.93
IUPAC Name: (S)-4-(2-(4-(5-chloro-2-(4-(trifluoromethyl)-1H-1,2,3-triazol-1-yl)phenyl)-5-methoxy-2-oxopyridin-1(2H)-yl)butanamido)-2-fluorobenzamide
InChIKey: XYWIPYBIIRTJMM-IBGZPJMESA-N
SMILES: COC(C(C1=C(N2C=C(N=N2)C(F)(F)F)C=CC(Cl)=C1)=C3)=CN([C@@H](CC)C(NC4=CC(F)=C(C=C4)C(N)=O)=O)C3=O
Biological Activity: Asundexian (BAY 2433334) is an orally active coagulation factor Xia (FXIa) inhibitor. Asundexian binds directly, potently, and reversibly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC50 of 1 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Asundexian | 99.80% | Asundexian (BAY 2433334) is an orally active coagulation factor Xia (FXIa) inhibitor. Asundexian binds directly, potently, and reversibly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC50 of 1 nM. | ||||||||||||||||||||
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Asundexian-d3 | Asundexian-d3 (BAY-2433334-d3) is the deuterium labeled Asundexian (HY-137431). Asundexian (BAY 2433334) is an orally active coagulation factor Xia (FXIa) inhibitor. Asundexian binds directly, potently, and reversibly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC50 of 1 nM. | |||||||||||||||||||||
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Similarity Score 1.00
HY-137431A(R)-Asundexian -
Similarity Score 0.59
HY-168712FXIa-IN-15 -
Similarity Score 0.52
HY-172400FXIa-IN-16 -
Similarity Score 0.51
HY-153817FXIa-IN-13 -
Similarity Score 0.49
HY-184822STAT6-IN-14 -
Similarity Score 0.48
HY-148259SF-1 antagonist-1 -
Similarity Score 0.47
HY-W1113770STAT6-IN-8 -
Similarity Score 0.47
HY-178128PSEN1-IN-3 -
Similarity Score 0.47
HY-50754gamma-secretase modulator 2 -
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